Company

Profile

 

Creaflow was founded in May 2018 and originates from a collaboration between EcoSynth and Ajinomoto Bio-Pharma Services. Its mission is to provide innovative and scalable flow reactors in order to address unmet needs for customers in the life science and chemical industry.

 

 

Operational Team

 

Koen Van Aken

Dr. Koen Van Aken

CEO

After obtaining a PhD at the Catholic University of Leuven (Belgium) in 1993, Koen Van Aken (°1965) occupied a postdoctoral position at Georgia State University, Atlanta. Afterwards, he returned to Belgium to join the Center of Molecular Design at Janssen Pharmaceutica (a division of Johnson & Johnson). As senior scientist, his work involved HIV drug design in close collaboration with Dr. Paul Janssen which eventually resulted in FDA approved drugs. After founding the company EcoSynth in 2001, he obtained a master in Innovation & Entrepreneurship at Vlerick Gent Management School (2007). His 23 years of experience in academic and industrial organic chemistry are illustrated by (co)authorship of over 40 publications (including 17 patents). Main interests include sustainable chemistry, flow chemistry, novel activation technologies, optimalization of reaction parameters, automation of organic chemistry and process development. As current guest professor, he teaches “sustainable chemistry” as a course at the Catholic University of Leuven, the same university at which he was appointed fellow of the faculty of science. He was also chairman of the feasibility study for the Flemish Initiative for Sustainable Chemistry and member of the former board of directors of FISCH, now transformed in CATALISTI.

Hannes Gemoets

Dr. ing. Hannes Gemoets

Head of R&D

Hannes P. L. Gemoets was born in Ghent (°1991), Belgium. In 2013, he received a M. Sc. degree in Chemical Engineering (cum laude) at the KU Leuven (Faculty of Engineering Technology Ghent). Later that year, he moved to the Netherlands to pursue his Ph.D. at the Eindhoven University of Technology (TU/e) in the Micro Flow Chemistry & Process Technology group, under the supervision of Prof. Timothy Noël and Prof. Volker Hessel. His research focused on the development of novel continuous-flow methods for C–H functionalization strategies (i.e. C–H activation and photoredox catalysis). As a next step in his career, Hannes joined the Research & Development division of Creaflow located in Deinze, Belgium. As Head of R&D, his work focusses on the on the design and development of innovative and scalable continuous-flow (photo)reactors, as well as the worldwide sales of the HANU reactor.

  

 

Scientific Advisory Board

 

Timothy Noël

Prof. Timothy Noël

Associate Professor

Eindhoven University of Technology

Timothy Noël received in 2004 his MSc degree (Industrial Chemical Engineering) from the KaHo Sint-Lieven in Ghent. He then moved to Ghent University to obtain a PhD at the Laboratory for Organic and Bioorganic Synthesis (2005-2009). Next, he moved to Massachusetts Institute of Technology (MIT) as a Fulbright Postdoctoral Fellow with Professor Stephen L. Buchwald. He currently holds a position as an associate professor and he chairs the Micro Flow Chemistry & Synthetic Methodology group at Eindhoven University of Technology. His research interests are flow chemistry, homogeneous catalysis and organic synthesis. His research on photochemistry in microfluidic reactors was awarded the DECHEMA award 2017.

Prof. Simon Kuhn

Associate Professor

KU Leuven

Simon Kuhn received his Diploma in Chemical Engineering from TU Munich and his PhD from ETH Zurich. After a stay as post-doctoral fellow at the Massachusetts Institute of Technology (MIT), he joined the Department of Chemical Engineering at University College London as assistant professor. In 2014, he was appointed as professor in the Department of Chemical Engineering at KU Leuven. His research interests lie in the characterization of transport processes in complex flows using experiments and modeling, scaling-up microchemical systems, and design of novel flow reactors.

Dr. Ir. Wouter Debrouwer

Senior Scientist

EcoSynth

Wouter Debrouwer (°1988) obtained his MSc in Bioscience Engineering, option chemistry and bioprocess technology, from Ghent University (Belgium, 2011). His PhD, under the supervision of professor Chris Stevens, included the development of synthetic entries toward azaheterocyclic organophosphonates and mechanistic investigations in the gold-catalyzed formation of benzothiophenes and was completed in 2015. Subsequently, he joined the group of prof. Alois Fürstner at the Max-Planck-Institut für Kohlenforschung (Mülheim an der Ruhr, Germany). His postdoctoral research involved the organometallic chemistry of gold carbenes and vinylidenes. In 2017 he joined Ecosynth as senior scientist specializing in continuous flow chemistry, photochemistry and chemical engineering. As such he was part of the R&D team that developed the HANU reactor.

Bert Metten 

Dr. Bert Metten

Technology Development Manager

Ajinomoto Bio-Pharma Services

Bert Metten (°1978) received his MSc in synthetic organic chemistry (Leuven University) in 2001 after studying the synthesis of macromolecules with fluorescent cores. His PhD (2005), under the supervision of professor Wim Dehaen, included synthetic entries towards non-nucleoside reverse transcriptase inhibitors (NNRTI) and low-affinity fluorescent Ca2+ indicators. He started working for Proctor and Gamble in 2005 finishing a project on macromolecular slow release systems. In 2006-2009 he was a senior scientist at Devgen (now Syngenta, Ghent) working on the synthesis of kinase inhibitors and ion channel inhibitors in the medicinal chemistry department. He started as research chemist at Ajinomoto Bio-Pharma Services (Wetteren) in 2009 and soon became head of the technology development group responsible for process research with innovative tools including biocatalysis, PAT, (photo)flow chemistry, membrane technology etc. As such he was co-inventor of the HANU reactor.

Dr. Dirk Van Deynse

Director R&D (retired)

Tessenderlo Chemie

Dirk Van Deynse obtained a PhD in Synthetic Organic Chemistry (Leuven University) in 1980, followed by a postdoctoral training at the Laboratory of Photochemistry at the same university. He started working for Tessenderlo Chemie in 1984 as a research chemist and became Manager of the newly build pilot plant in 1989, and four years later “Chief Engineer” responsible for the development and optimization of production processes. In 1999 he was appointed director of R&D and was accepted as board member of different affiliates of the group (in Belgium, UK, Italy and China). He ended his career as Business Unit Manager of Organic Chlorinated Derivatives, and retired in November 2014.